Revolutionizing Research: Chimeric Molecules and Genetic Engineering Break New Ground in Science

Half a century ago, chimeras provided a sneak peek into the future of gene editing

Advancements in gene-editing technology have enabled scientists to create chimeric molecules made up of genes from different sources, including animals and bacteria. This process allows animal genes to replicate within the bacterium, opening up new possibilities for genetic research and potential applications in correcting genetic defects.

Recent experiments have expanded beyond bacteria, with scientists successfully creating mouse embryos with human cells, developing brains composed of rat and mouse cells, and growing human organs in pigs. In a groundbreaking procedure, surgeons transplanted a genetically modified pig kidney into a human patient in Boston. By removing certain pig genes and adding human genes to enhance compatibility with the human immune system, the patient was able to receive the kidney. Although the patient passed away from an unrelated cause, the success of this transplant opens up new possibilities for organ transplantation.

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