A team of researchers led by Prof. Dr. Dinh Thi Mai Thanh at the University of Science and Technology Hanoi (USTH), Vietnam Academy of Science and Technology, have successfully developed a new drug-carrying material that effectively kills 75% of bladder cancer cells. The material, called a “superparamagnetic hybrid,” is made up of superparamagnetic iron oxide nanoparticles (SPIONs) and hydroxyapatite (HAp), which increase magnetic heat and can carry drugs efficiently.
The material’s core consists of SPIONs surrounded by HAp with pores that carry drugs through adsorption. By immobilizing the anti-cancer drug 5-FU, this material can kill bladder cancer cells by releasing the drugs locally. When combined with copper (Cu) and introduced into the body, under the effect of an external magnetic field, the SPIONs nanoparticles increase magnetic heat, releasing therapeutic drugs and killing cancer cells effectively.
Professor Mai Thanh highlights the importance of combining magnetic hyperthermia with anti-cancer agents in destroying cancer cells. This material has shown to be effective in killing cancer cells up to 75%. The team is currently testing it on other types of cancer cells such as ovarian and liver cancer to explore its full potential.
Professor Mai Thanh’s research journey focuses on developing advanced materials for medical applications with a particular interest in combining traditional biomedical materials with new technologies. Her dedication to advancing research in biomedical technology highlights the importance of interdisciplinary collaboration in the field. With expertise in chemistry and years of research experience, she aims to contribute to advancements in healthcare and medicine in Vietnam and beyond.
In conclusion, Prof. Mai Thanh’s team has successfully synthesized a new drug-carrying material capable of killing 75% of bladder cancer cells using magnetic hyperthermia combined with anti-cancer agents. Their work has opened up new avenues for research into innovative therapies for various types of cancers, highlighting the importance of interdisciplinary collaboration in biomedical technology.
